Chronic stress promotes breast cancer. Here's how

Deesha Bondre | Apr 10, 2019, 17:30 IST


While we all knew stress was bad, a recent Chinese study just informed us how bad it can be. According to a group of Chinese researchers said that the mechanisms of chronic stress is conducive to breast cancer development and shed more light on future clinical treatment for cancer.
Anxiety, depression and other negative emotions like despair and fear are common among cancer patients- which also increase the risk for tumour growth as well go on promoting cancer progression in the body. But the study hasn’t been able to figure out how chronic stress has an effect on cancer development.
The research team that comes from the Dalian Medical University in China found that chronic stress can increase epinephrine levels, which also enhances lactate dehydrogenase A (LDHA) and furthers the growth of breast cancer cells.
A drug screen was used to target LDHA and found that Vitamin C reserved the chronic stress-induced cancer stem-like phenotype.
Apart from the this the study also demonstrated the importance of psychological facts that promote stem-like properties in breast cancer cells and provide a promising therapeutic approach for breast cancer, according to Liu Qiang, the lead researcher at the varsity.
“The LDHA-lowering agent Vitamin C can be a potential approach for combating stress-associated breast cancer,” Qiang said, in the paper published in the Journal of Clinical Investigation.
The engaged in the dynamic regulation of cancer stem cells research as well as the mechanism of psychosocial behavior affecting tumour development.
Qiang noted that patients with breast cancer, ovarian cancer, and stomach cancer often have negative emotions, which in turn accelerates the development of their own tumours.
“It is necessary to monitor their chronic stress comprehensively by taking psychological assessments as well as conducting blood tests which include epinephrine levels,” Qiang said.

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